Tri-ortho-cresyl phosphate induces autophagy of mouse ovarian granulosa cells

Involvement of oxidative stress in tri-ortho–cresyl phosphate-induced autophagy of mouse Leydig TM3 cells in vitro

BACKGROUND As a plasticizer, plastic softener, and flame-retardant, tri-ortho-cresyl phosphate (TOCP) is and has been widely used in industry and reported to have a toxic effect on the male reproductive system in animals besides neurotoxicity and immunotoxicity. We have reported that TOCP inhibits spermatogenesis and induces autophagy of rat spermatogonial stem cells, but it is still unknown wh...

[A case of tri-ortho-cresyl-phosphate poisoning].

Interim Specific Ground Water Criterion - Tri-ortho-cresyl phosphate (TOCP)

An outbreak of tri-ortho-cresyl phosphate (T.O.C.P.) poisoning in Durban.

Tri-ortho-cresyl phosphate (T.O.C.P.) is an organic phosphorus compound commonly used in industry as a plasticizer, and is so used in the manufacture of lacquers, dopes, synthetic fabrics, and synthetic lignin resin; it is used as a water-proofing agent in textile manufacture. It is said to be an excellent grinding medium for pigments; it is also used in making polyvinyl chloride sheeting and f...

The absorption of tri-ortho-cresyl phosphate through the skin of hens and its neurotoxic effects.

General and neurotoxic effects of ingested triortho-cresyl phosphate *(TOCP) in man and animals have been described in detail for the last 20 years. We refer here only briefly to the clinical literature where TOCP was implicated, such as Jamaica ginger paralysis in America (Aring, Bean, Roseman, Rosenbaum, and Spies, 1941; Aring, 1942); the massive intoxications by engine oil at the beginning o...